Fabrication and characterization of dipalmitoylphosphatidylcholine-attracting elastomeric material for joint replacements
| Autor: | Brian J. Love, P.F. Williams, Martine LaBerge, Kazuhiko Ishihara, Nobuo Nakabayashi, G L Powell, R. Johnson |
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| Rok vydání: | 1995 |
| Předmět: |
Fabrication
Materials science 1 2-Dipalmitoylphosphatidylcholine Polyurethanes Biophysics Bioengineering Elastomer law.invention Biomaterials chemistry.chemical_compound law Bearing (mechanical) Electron Spin Resonance Spectroscopy Spectrometry X-Ray Emission Biomaterial Polyethylene Tribology Biomechanical Phenomena Spectrometry Fluorescence chemistry Mechanics of Materials Cushion Ceramics and Composites Lubrication Hip Prosthesis Rubber Biomedical engineering |
| Zdroj: | Biomaterials. 16:1169-1174 |
| ISSN: | 0142-9612 |
| Popis: | Wear debris associated with the polyethylene components of total joint replacements has been shown to induce bone resorption which contributes to implant loosening. In an effort to promote lubrication and reduce wear in artificial hip joints, the use of the cushion bearing concept has been proposed previously; however, an elastomeric material tested as a cushion bearing has been shown to have poor tribological properties during initiation of motion from rest. The goal of this project was to fabricate and characterize an elastomer that has the ability to attract to its surface naturally occurring boundary lubricants from an aqueous solution. The test elastomer and appropriate controls were characterized using fluorescence, electron spin resonance and X-ray photoelectron spectroscopy. The test elastomer was found to have an enhanced ability to attract dipalmitoylphosphatidylcholine, a known physiological boundary lubricant. A cushion bearing that also encourages boundary lubrication represents a potential improvement over currently existing orthopaedic implant-bearing materials. |
| Databáze: | OpenAIRE |
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