Upper Respiratory Tract Co-detection of Human Endemic Coronaviruses and High-density Pneumococcus Associated With Increased Severity Among HIV-Uninfected Children Under 5 Years Old in the PERCH Study

Autor: Grant A. Mackenzie, Laura L. Hammitt, Orin S. Levine, Karen L. Kotloff, Maria Deloria Knoll, Christine Prosperi, Wantana Paveenkittiporn, Juliet O. Awori, Donald M. Thea, Susan C. Morpeth, Vicky L. Baillie, Lawrence Mwananyanda, Steve R C Howie, Henry C. Baggett, David R. Murdoch, J. Anthony G. Scott, Samba O. Sow, Daniel E. Park, Daniel R. Feikin, W. Abdullah Brooks, Katherine L. O'Brien, Charatdao Bunthi, Shabir A. Madhi, Geoffrey Kwenda, Mohammed Ziaur Rahman, David P. Moore, Melissa M Higdon, Martin Antonio, Milagritos D. Tapia, Mustafizur Rahman, Julia Rhodes
Rok vydání: 2021
Předmět:
Microbiology (medical)
Male
medicine.medical_specialty
viruses
coronavirus
HIV Infections
medicine.disease_cause
Logistic regression
Gastroenterology
Pneumococcal Infections
Original Studies
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
Internal medicine
Nasopharynx
Streptococcus pneumoniae
medicine
Animals
Humans
030212 general & internal medicine
Respiratory system
Respiratory Tract Infections
Coronavirus
business.industry
Coinfection
SARS-CoV-2
Infant
Newborn
COVID-19
Infant
Pneumonia
medicine.disease
respiratory tract diseases
Infectious Diseases
medicine.anatomical_structure
Logistic Models
Child
Preschool
Pediatrics
Perinatology and Child Health
Etiology
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING
Female
business
Coronavirus Infections
pneumococcus
Respiratory tract
Zdroj: The Pediatric Infectious Disease Journal
ISSN: 1532-0987
0891-3668
Popis: Supplemental Digital Content is available in the text.
Background: Severity of viral respiratory illnesses can be increased with bacterial coinfection and can vary by sex, but influence of coinfection and sex on human endemic coronavirus (CoV) species, which generally cause mild to moderate respiratory illness, is unknown. We evaluated CoV and pneumococcal co-detection by sex in childhood pneumonia. Methods: In the 2011–2014 Pneumonia Etiology Research for Child Health study, nasopharyngeal and oropharyngeal (NP/OP) swabs and other samples were collected from 3981 children
Databáze: OpenAIRE
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