Association between infertility and mental health of offspring in the United States: a population based cohort study
| Autor: | Chiyuan A. Zhang, Michael L. Eisenberg, Barbara Luke, Alex Kasman |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Infertility
medicine.medical_specialty 030219 obstetrics & reproductive medicine Offspring business.industry Vasectomy Obstetrics and Gynecology 030209 endocrinology & metabolism General Medicine medicine.disease Mental health Odds 03 medical and health sciences 0302 clinical medicine Reproductive Medicine Epidemiology Intellectual disability medicine Autism business Demography |
| Zdroj: | Human Fertility. 25:384-389 |
| ISSN: | 1742-8149 1464-7273 |
| DOI: | 10.1080/14647273.2020.1805799 |
| Popis: | There exist conflicting data in regard to the health outcomes of offspring born to infertile couples and follow up of offspring can be challenging. The objective of the study was to determine the association between infertility in men and women and the mental health of their offspring. The present study analyzes data obtained from the IBM Marketscan™ Commercial Claims and Encounters database from 2007 through 2015. Overall, 271,603 children of males with male factor infertility, 328,571 children of females with female factor infertility, 663,568 children of males who later underwent vasectomy were identified. The odds of psychosis were increased in offspring of those with male factor infertility (OR 1.25, 95% CI 1.22-1.29) and female factor infertility (OR 1.20, 95% CI 1.17-1.23). Offspring of infertile males (OR 1.19, 95% CI 1.13-1.26) and infertile females (OR 1.20, 95% CI 1.14-1.26) had an increased odds of autism compared to the reference group. In addition, offspring of infertile males (OR 1.48, 95% CI 1.28-1.7) and infertile females (OR 1.52, 95% CI 1.33-1.73) had higher odds of being diagnosed with an intellectual disability. Therefore, offspring of infertile men or women may have an increased risk of developing psychosis, autism, or intellectual disability. |
| Databáze: | OpenAIRE |
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