Osteochondral Allografts in Knee Surgery: Narrative Review of Evidence to Date

Autor:	Wilson C Lai, Hunter L Bohlen, Nathan P Fackler, Dean Wang
Rok vydání:	2022
Předmět:	Transplantation Arthritis Pain Research Rehabilitation Clinical Sciences Evaluation of treatments and therapeutic interventions Organ Transplantation outcomes Physical Rehabilitation Clinical Research Musculoskeletal 5.4 Surgery osteochondral allograft transplantation Orthopedics and Sports Medicine Chronic Pain Development of treatments and therapeutic interventions cartilage survivorship 6.4 Surgery
Zdroj:	Orthopedic Research and Reviews. 14:263-274
ISSN:	1179-1462
DOI:	10.2147/orr.s253761
Popis:	Knee articular cartilage defects can result in significant pain and loss of function in active patients. Osteochondral allograft (OCA) transplantation offers a single-stage solution to address large chondral and osteochondral defects by resurfacing focal cartilage defects with mature hyaline cartilage. To date, OCA transplantation of the knee has demonstrated excellent clinical outcomes and long-term survivorship. However, significant variability still exists among clinicians with regard to parameters for graft acceptance, surgical technique, and rehabilitation. Technologies to optimize graft viability during storage, improve osseous integration of the allograft, and shorten recovery timelines after surgery continue to evolve. The purpose of this review is to examine the latest evidence on treatment indications, graft storage and surgical technique, patient outcomes and survivorship, and rehabilitation after surgery.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3556fe7c22216e9bbf047b0f41f9fce https://doi.org/10.2147/orr.s253761 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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