Rare case of intramedullary spinal cord metastasis from nasopharyngeal carcinoma
| Autor: | Rich Ericson C. King, Marjorie Anne C. Bagnas, Cyril Jonas M. Planilla, Marvin Jonne L. Mendoza, Sheen Corvera Urquiza, Anisah Hayaminnah D. Alonto, Mark Willy L. Mondia |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male Cancer Research medicine.medical_specialty medicine.medical_treatment Philippines Metastasis 03 medical and health sciences 0302 clinical medicine medicine Humans Spinal Cord Neoplasms Stage (cooking) Stroke Nasopharyngeal Carcinoma medicine.diagnostic_test Urinary retention business.industry Magnetic resonance imaging Nasopharyngeal Neoplasms Middle Aged medicine.disease Spinal cord Radiation therapy 030104 developmental biology medicine.anatomical_structure Treatment Outcome Oncology Nasopharyngeal carcinoma 030220 oncology & carcinogenesis Carcinoma Squamous Cell Radiology medicine.symptom business |
| Zdroj: | Current problems in cancer. 45(6) |
| ISSN: | 1535-6345 |
| Popis: | Introduction Central nervous system (CNS) metastasis from nasopharyngeal carcinoma (NPC) is rare and presents with high morbidity and mortality. As a rare entity, a few patients with CNS metastasis from NPC have been reported, and no studies were available on treatment and prognosis. Based on our clinical experience, early diagnosis with incorporation of a clear palliative plan is imperative in providing holistic care for patients with locally-invasive and metastatic nasopharyngeal carcinoma. Case report Our study reports a case of a 48-year-old Filipino male with known NPC Stage IVB who developed acute symptoms of constipation, urinary retention, and bilateral lower limb weakness and numbness. Magnetic resonance imaging showed intramedullary lesions in multiple segments of the spinal cord. Steroid and radiotherapy of the spine were initiated with noted transient improvement of the motor strength. Subsequently, he developed cancer-related stroke. The patient progressively deteriorated despite best medical care. |
| Databáze: | OpenAIRE |
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