Identification of post-translationally modified proteins in proteome studies

Autor: Elke Butt-Dörje, Armin Herkner, Katrin Marcus, Heike Schäfer, Inke Bahr, Silke Suer, Stefan Lehr, Albert Sickmann, Helmut E. Meyer
Rok vydání: 2001
Předmět:
Zdroj: ELECTROPHORESIS. 22:1669-1676
ISSN: 1522-2683
0173-0835
DOI: 10.1002/1522-2683(200105)22:9<1669::aid-elps1669>3.0.co;2-7
Popis: Proteome studies are powerful tools to solve many different problems in metabolism, signal transduction, drug discovery, and other areas of interest in life sciences. Up to now, high-sensitive methods for protein identification after two-dimensional gel electrophoresis using mass spectrometry are available. However, the identification of post-translational modifications after two-dimensional gel electrophoresis is still an unsolved problem. In this paper, we want to give several examples for the successful identification of post-translational modifications and point mutations.
Databáze: OpenAIRE
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