Percutaneous microwave coagulation therapy in liver tumors
| Autor: | M. Takahashi, Joji Urata, S. Yoshimatsu, Akihiko Arakawa, Taiji Nishiharu, Tetsuya Matsukawa, R. Murakami, Yasuyuki Yamashita |
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| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Carcinoma Hepatocellular Percutaneous Fever medicine.medical_treatment Skin Diseases Electrocoagulation Metastasis Neoplasm Seeding medicine Humans Radiology Nuclear Medicine and imaging Microwave coagulation therapy Microwaves Electrodes Ultrasonography Interventional Aged Aged 80 and over Hematoma Pain Postoperative Radiological and Ultrasound Technology business.industry Liver Neoplasms Remission Induction General Medicine Middle Aged medicine.disease Surgery Survival Rate Ultrasound guidance Treatment Outcome Hepatocellular carcinoma Female Radiology Tomography X-Ray Computed business Follow-Up Studies |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1080/02841859709172092 |
| Popis: | Purpose: Percutaneous microwave coagulation therapy (PMCT) is an interventional alternative for inoperable malignant liver tumors. in this paper, we report the results of our 3-year experience of PMCT in order to establish suitable indications for this treatment. Material and Methods: We studied a total of 27 inoperable liver tumors in 24 patients. Histology of the tumors showed 20 hepatocellular carcinomas (HCCs) (13 well differentiated, 4 moderately differentiated, and 3 poorly differentiated) and 7 metastases. These tumors were treated by PMCT and were followed for 4–40 months (average 18 months). Under US guidance, the tumors were coagulated by microwaves emitted from an electrode. the changes of tumor size after PMCT were evaluated by CT. When the tumors disappeared or were reduced in size after treatment, PMCT was regarded as effective. Complications from PMCT were also evaluated. the patient survival rate was obtained by means of the Kaplan-Meier method. Results: in tumors of 30 mm or less, treatment response was obtained in 70% of cases, while 55% of tumors larger than 30 mm responded. the tumor became smaller or disappeared in 85% of the well differentiated HCCs, and in 25% of the moderately differentiated HCCs, but none of the poorly differentiated HCCs responded. in metastatic tumors, PMCT was effective in 57% of cases, Slight pain (24%), fever (20%) and subcutaneous hematoma (8%) were experienced immediately after PMCT. in 2 poorly differentiated HCCs, needle tract seeding was observed. No case of liver dysfunction was seen after PMCT. the overall survival rate was 83.1% at 1 year and 68.7% at 2 years. Conclusion: Good therapeutic results were achieved with PMCT in lesions of 30 mm or less, and in well differentiated HCCs. |
| Databáze: | OpenAIRE |
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