Transmission of Antimicrobial-Resistant Staphylococcus aureus Clonal Complex 9 between Pigs and Humans, United States
Autor: | Hülya Kaya, Jill R. Stewart, Meghan F. Davis, Karen C. Carroll, Trish M. Perl, Devon Hall, Lloyd S. Miller, Maliha Aziz, Nora Pisanic, Dave C. Love, David Mohr, Jesper Larsen, Maya Nadimpalli, Lance B. Price, Carly Ordak, Christopher D. Heaney, Pranay R. Randad, Sarah M. Rhodes |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Swine
Epidemiology lcsh:Medicine MRSA and other staphylococci zoonotic transmission medicine.disease_cause law.invention 0302 clinical medicine Data sequences law AMR 030212 general & internal medicine Animal Husbandry bacteria Clade Phylogeny Phylogenetic tree industrial hog operations livestock-associated diseases pigs Staphylococcal Infections Antimicrobial Anti-Bacterial Agents food safety Infectious Diseases Transmission (mechanics) Multidrug resistant bacteria Staphylococcus aureus Methicillin-Resistant Staphylococcus aureus Microbiology (medical) Livestock 030231 tropical medicine multidrug-resistant bacteria Biology Microbiology lcsh:Infectious and parasitic diseases 03 medical and health sciences Antibiotic resistance North Carolina medicine Animals Humans lcsh:RC109-216 antimicrobial resistance Research lcsh:R infectious disease transmission United States zoonoses Transmission of Antimicrobial-Resistant Staphylococcus aureus Clonal Complex 9 between Pigs and Humans United States |
Zdroj: | Emerging Infectious Diseases, Vol 27, Iss 3, Pp 740-748 (2021) Emerging Infectious Diseases |
ISSN: | 1080-6059 1080-6040 |
Popis: | Transmission of livestock-associated Staphylococcus aureus clonal complex 9 (LA-SA CC9) between pigs raised on industrial hog operations (IHOs) and humans in the United States is poorly understood. We analyzed whole-genome sequences from 32 international S. aureus CC9 isolates and 49 LA-SA CC9 isolates from IHO pigs and humans who work on or live near IHOs in 10 pig-producing counties in North Carolina, USA. Bioinformatic analysis of sequence data from the 81 isolates demonstrated 3 major LA-SA CC9 clades. North Carolina isolates all fell within a single clade (C3). High-resolution phylogenetic analysis of C3 revealed 2 subclades of intermingled IHO pig and human isolates differing by 0–34 single-nucleotide polymorphisms. Our findings suggest that LA-SA CC9 from pigs and humans share a common source and provide evidence of transmission of antimicrobial-resistant LA-SA CC9 between IHO pigs and humans who work on or live near IHOs in North Carolina. |
Databáze: | OpenAIRE |
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