Early results of MitraClip system implantation by real-time three-dimensional speckle-tracking left ventricle analysis
| Autor: | Carmelo Grasso, Margherita Ministeri, Sarah Mangiafico, Fabio Dipasqua, Antonio Arcidiacono, Salvatore Scandura, Stefano Cannata, Sebastiano Immè, Marta Chiarandà, Corrado Tamburino, Piera Capranzano, Anna Caggegi, Giuseppe Ronsivalle, Giuseppe Gargiulo, Davide Capodanno, Anna Maria Pistritto |
|---|---|
| Přispěvatelé: | Scandura, S., Dipasqua, F., Gargiulo, G., Capodanno, D., Caggegi, A., Grasso, C., Mangiafico, S., Pistritto, A. M., Imme, S., Chiaranda, M., Ministeri, M., Ronsivalle, G., Cannata, S., Arcidiacono, A. A., Capranzano, P., Tamburino, C. |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Cardiac output Heart Ventricles medicine.medical_treatment Echocardiography Three-Dimensional MitraClip system 030204 cardiovascular system & hematology Ventricular Function Left Real-time three-dimensional echocardiography Heart Ventricle 03 medical and health sciences 0302 clinical medicine Internal medicine Mitral valve medicine Humans 030212 general & internal medicine Mitral regurgitation Speckle tracking Aged Aged 80 and over Mitral valve repair Ejection fraction business.industry MitraClip Mitral Valve Insufficiency Stroke Volume General Medicine Stroke volume Left ventricular deformation Treatment Outcome medicine.anatomical_structure Surgical Fixation Device Ventricle Surgical Fixation Devices Cardiology Mitral Valve Female Cardiology and Cardiovascular Medicine business Human |
| Zdroj: | Journal of Cardiovascular Medicine. 17:843-849 |
| ISSN: | 1558-2027 |
| DOI: | 10.2459/jcm.0000000000000284 |
| Popis: | Aims To appraise the early effect of percutaneous mitral valve repair with the MitraClip system on myocardial function using real-time three-dimensional speckle-tracking echocardiography (3D-STE). Methods Consecutive patients with moderate-to-severe or severe mitral regurgitation, undergoing mitral valve repair with the MitraClip system, were prospectively evaluated during the peri-procedural workout and follow-up. Left ventricular deformation was evaluated by a two-dimensional and 3D speckle-tracking analysis. 3D-STE acquisitions were elaborated obtaining real-time 3D global longitudinal strain evaluation, and by appraising both volumetric and hemodynamic parameters (i.e. left ventricular end-diastolic volume, left ventricular end-systolic volume, left ventricular ejection fraction, cardiac output, and stroke volume). Results In all, 30 patients were included. At 1-month follow-up, 3D-STE analysis revealed no changes in left ventricular end-diastolic volume (162.6 ± 73.7 ml at baseline vs. 159.8 ± 64.5 ml at 1-month follow-up; P = 0.63) and a downward trend in left ventricular end-systolic volume (104.7 ± 52.0 vs. 100.1 ± 50.4 ml, respectively; P = 0.06). Left ventricular ejection fraction did not significantly increase (38.1 ± 11.3% at baseline vs. 39.4 ± 11.0% at 1-month follow-up; P = 0.20). No significant changes were reported in cardiac output (4.3 ± 2.0 l/min at baseline vs. 4.0 ± 1.5 l/min at follow-up; P = 0.377) and in stroke volume (59.5 ± 25.5 ml at baseline vs. 59.9 ± 20.7 ml at follow-up; P = 0.867). On the contrary, left ventricular deformation capability significantly improved, with the real-time 3D global longitudinal strain value changing from -9.8 ± 4.1% at baseline to -11.0 ± 4.4% at follow-up (P = 0.018). Conclusions Accurately assessing myocardial function by the use of 3D-STE, this study reported irrelevant early changes in left ventricular size, but a positive effect on left ventricular deformation capability following mitral valve repair with the MitraClip system. These preliminary results need to be confirmed in larger series and extended to long-term follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|