Breast Metastasis of Gastric Signet Ring Cell Carcinoma: A Case Report and Literature Review
| Autor: | Lilian Mónica Navarro-García, Ricardo Fernández-Ferreira, Andres Macari-Jorge, Ildefonso Roberto De la Peña-López, Héctor Hugo Buerba-Vieregge, Pamela Denisse Soberanis-Piña |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty breast metastasis medicine.medical_treatment Case Report chemotherapy lcsh:RC254-282 Ramucirumab 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Signet ring cell carcinoma Medicine gastric carcinoma skin and connective tissue diseases Chemotherapy medicine.diagnostic_test Signet ring cell business.industry signet ring cell Cancer medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens digestive system diseases Irinotecan 030104 developmental biology Oncology Paclitaxel chemistry Positron emission tomography 030220 oncology & carcinogenesis business medicine.drug |
| Zdroj: | Case Reports in Oncology, Vol 14, Iss 1, Pp 165-172 (2021) Case Reports in Oncology |
| ISSN: | 1662-6575 |
| Popis: | Breast metastasis from gastric signet ring cell carcinoma is extremely rare in clinical practice. The estimated incidence is 0.5–1.3%. There are few cases reported in the literature (approx. less than 60) of breast metastasis from gastric signet ring cell carcinoma, and due to the rare association between gastric cancer and its extension to the breast, it is difficult to establish the diagnosis. Clinical history, histological findings, and immunohistochemical markers are helpful in distinguishing primary breast cancer from breast metastasis of gastric cancer. The treatment for breast metastasis from gastric carcinoma remains controversial. The prognosis of breast metastasis from gastric carcinoma is generally poor. We report a case of breast metastasis of gastric signet ring cell carcinoma in a 38-year-old woman. She started chemotherapy with ramucirumab, paclitaxel, and irinotecan. Three months later, a combined 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography showed a complete response. This is the first reported case of breast metastasis from gastric signet ring cell carcinoma with a complete response. |
| Databáze: | OpenAIRE |
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