Trends in cervical cancer incidence and mortality in Bulgaria, Estonia, Latvia, Lithuania and Romania
| Autor: | Zdravka Valerianova, Giedre Smailyte, Marc Arbyn, Margit Mägi, Andrea Micheli, Aivars Stengrevics, Jerome Antoine, Ofelia Suteu |
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| Předmět: |
Adult
Estonia Cancer Research Uterine Cervical Neoplasms 03 medical and health sciences Age Distribution 0302 clinical medicine Environmental protection Uterine cancer medicine Humans Mass Screening media_common.cataloged_instance 030212 general & internal medicine European union Bulgaria Survival rate Mass screening Aged media_common Aged 80 and over Cervical cancer Romania business.industry Incidence Mortality rate Incidence (epidemiology) Lithuania General Medicine Middle Aged medicine.disease Latvia Survival Rate Oncology 030220 oncology & carcinogenesis Cohort Female business Demography |
| Zdroj: | Scopus-Elsevier |
| Popis: | Objective The burden of cervical cancer varies considerably in the European Union. In this paper, we describe trends in incidence of and mortality from this cancer in the five most affected member states. Methods Data on number of deaths from uterine cancers and the size of the female population of Estonia, Latvia, Lithuania, Bulgaria and Romania were extracted from the WHO mortality database. Mortality rates were corrected for inaccuracies in the death certification of not otherwise specified uterine cancer. Incidence data were obtained from the national cancer registries. Joinpoint regression was used to study the annual variation of corrected and standardized incidence and mortality rates. Changes by birth cohort were assessed for specific age groups and subsequently synthesized by computing standardized cohort incidence/mortality ratios. Results Joinpoint regression revealed rising trends of incidence (in Lithuania, Bulgaria and Romania) and of mortality (in Latvia, Lithuania, Bulgaria and Romania). In Estonia, rates were rather stable. Women born between 1940 and 1960 were at continuously increasing risk of both incidence of and mortality from cervical cancer. Conclusions Rising trends of cervical cancer in the most affected EU member states reveal a worrying pattern that warrants urgent introduction of effective preventive actions as described in the European guidelines. |
| Databáze: | OpenAIRE |
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