Etanercept-Induced Hypoglycemia in a Patient With Psoriatic Arthritis and Diabetes
| Autor: | Emily C. Pfeifer, David Saxon, R W Janson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Axial skeleton Epidemiology Inflammatory arthritis 030209 endocrinology & metabolism Inflammation Case Report Hypoglycemia Etanercept 03 medical and health sciences Psoriatic arthritis 0302 clinical medicine Psoriasis Diabetes mellitus medicine lcsh:Pathology Safety Risk Reliability and Quality 030203 arthritis & rheumatology psoriatic arthritis lcsh:R5-920 business.industry medicine.disease Dermatology medicine.anatomical_structure hypoglycemia diabetes mellitus medicine.symptom business lcsh:Medicine (General) Safety Research etanercept medicine.drug lcsh:RB1-214 |
| Zdroj: | Journal of Investigative Medicine High Impact Case Reports, Vol 5 (2017) Journal of Investigative Medicine High Impact Case Reports |
| ISSN: | 2324-7096 |
| Popis: | Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis and inflammation involving the axial skeleton and/or peripheral joints. It is more likely to be associated with metabolic syndrome and diabetes when compared with other inflammatory arthritides. Tumor necrosis factor-α (TNF-α) is one of several cytokines often elevated in rheumatologic disorders including PsA and has also been found to be elevated in patients with obesity, metabolic syndrome, diabetes, and/or atherosclerotic disease. We describe the case of a patient with PsA as well as poorly controlled type 2 diabetes mellitus who experienced not only improvement in his psoriasis and arthritis with the anti-TNF-α agent etanercept but also recurrent hypoglycemia and significant improvement in hemoglobin A1c despite discontinuation of all conventional therapy for diabetes. |
| Databáze: | OpenAIRE |
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