Cell renewal of the rat corneal epithelium
| Autor: | Erling Håskjold, Sigvald B. Refsum, Rolf Bjerknes |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Basement membrane
Conjunctiva genetic structures Cell Mitosis Mitotic rate Cell Count Epithelial Cells Rats Inbred Strains General Medicine Anatomy Biology eye diseases Rats Cornea Ophthalmology medicine.anatomical_structure Proliferation rate Methods medicine Animals sense organs Corneal epithelium |
| Zdroj: | Acta Ophthalmologica. 66:533-537 |
| ISSN: | 1755-375X |
| DOI: | 10.1111/j.1755-3768.1988.tb04376.x |
| Popis: | A stathmokinetic method to study the mitotic rate in the corneal epithelium of the rat is described and applied. Horizontal and vertical diameter sections were used. In order to analyze the mitotic rate in the various parts of the corneal epithelium, each vision field (objective 100, eye piece 12.5), comprising 182 microns basement membrane, was regarded as a separate unit. Since the number of vision fields across the cornea varies from specimen to specimen, we constructed a mathematical method to correlate corresponding corneal areas from different eyes. Using this method it is shown that the mitotic rate is almost equal all over the cornea, with no definite reduction in the central areas. There is no area of significantly high proliferation rate, either in the limbal area or in the adjacent conjunctiva. |
| Databáze: | OpenAIRE |
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