Diagnostic criteria for early hip osteoarthritis: First steps, based on the CHECK study

Autor: Runhaar, J., Ozbulut, O., Kloppenburg, M., Boers, M., Bijlsma, J.W.J., Bierma-Zeinstra, S.M.A., CREDO Expert Grp
Přispěvatelé: Epidemiology and Data Science, AII - Inflammatory diseases, APH - Methodology, General Practice, Orthopedics and Sports Medicine, Orthopaedic Biomechanics
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Rheumatology (Bulgaria), 60(11), 5158-5164. Meditsiinski Unversitet-Sofia
Rheumatology (Oxford, England)
Rheumatology, 60(11), 5158-5164. OXFORD UNIV PRESS
Runhaar, J, Özbulut, Ö, Kloppenburg, M, Boers, M, Bijlsma, J W J & Bierma-Zeinstra, S M A 2021, ' Diagnostic criteria for early hip osteoarthritis : First steps, based on the CHECK study ', Rheumatology (Bulgaria), vol. 60, no. 11, pp. 5158-5164 . https://doi.org/10.1093/rheumatology/keab111
Rheumatology (Oxford, England), 60(11), 5158-5164. Oxford University Press
Rheumatology (Bulgaria), 60(11), 5158-5164
ISSN: 1310-0505
1462-0332
1462-0324
Popis: Objectives Although there is a general focus on early diagnosis and treatment of hip OA, there are no validated diagnostic criteria for early-stage hip OA. The current study aimed to take the first steps in developing diagnostic criteria for early-stage hip OA, using factors obtained through history taking, physical examination, radiography and blood testing at the first consultation in individuals presenting with hip pain, suspicious for hip OA, in primary care. Methods Data of the 543 individuals with 735 symptomatic hips at baseline who had any follow-up data available from the prospective CHECK cohort study were used. A group of 26 clinical experts [general practitioners (GPs), rheumatologists and orthopaedic surgeons] evaluated standardized clinical assessment forms of all subjects on the presence of clinically relevant hip OA 5–10 years after baseline. Using the expert-based diagnoses as reference standard, a backward selection method was used to create predictive models based on pre-defined baseline factors from history taking, physical examination, radiography and blood testing. Results Prevalence of clinically relevant hip OA during follow-up was 22%. Created models contained four to eight baseline factors (mainly WOMAC pain items, painful/restricted movements and radiographic features) and obtained area under the curve between 0.62 (0.002) and 0.71 (0.002). Conclusion Based on clinical and radiographic features of hip OA obtained at first consultation at a GP for pain/stiffness of the hip, the prediction of clinically relevant hip OA within 5–10 years was ‘poor’ to ‘fair’.
Databáze: OpenAIRE