Adverse Drug Reactions in a Tertiary Care Emergency Medicine Ward - Prevalence, Preventability and Reporting

Autor: Lennart Holm, Ida Engqvist, Jonatan D. Lindh, Jessica Fryckstedt, Charlotte Asker-Hagelberg, Carl-Olav Stiller, Diana M. Rydberg
Rok vydání: 2016
Předmět:
Male
Critical Care and Emergency Medicine
Medical Doctors
Cross-sectional study
Health Care Providers
lcsh:Medicine
Pathology and Laboratory Medicine
030226 pharmacology & pharmacy
Tertiary care
Vascular Medicine
Tertiary Care Centers
0302 clinical medicine
Prevalence
Medicine and Health Sciences
Medicine
030212 general & internal medicine
Prospective Studies
Prospective cohort study
lcsh:Science
Diuretics
Aged
80 and over

Multidisciplinary
Pharmaceutics
Drugs
Middle Aged
University hospital
Hospitals
Professions
Adr reporting
Antihypertensive Drugs
Female
Emergency Service
Hospital

Research Article
medicine.medical_specialty
Beta-Adrenergic Antagonist Therapy
Drug-Related Side Effects and Adverse Reactions
MEDLINE
Hemorrhage
03 medical and health sciences
Signs and Symptoms
Drug Therapy
Diagnostic Medicine
Physicians
Adverse Drug Reaction Reporting Systems
Humans
Drug reaction
Aged
Sweden
Pharmacology
business.industry
lcsh:R
Health Care
Cross-Sectional Studies
Health Care Facilities
Emergency medicine
People and Places
Observational study
lcsh:Q
Population Groupings
business
Anxiolytics
Receptor Antagonist Therapy
Zdroj: PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162948 (2016)
ISSN: 1932-6203
Popis: Purpose To identify the prevalence and preventability of adverse drug reactions (ADRs) in an emergency ward setting in a tertiary hospital in Sweden and to what extent the detected ADRs were reported to the Medical Product Agency (MPA). Methods In this prospective cross sectional observational study, 706 patients admitted to one of the Emergency Wards, at the Karolinska University Hospital in Solna, Stockholm during September 2008 –September 2009, were included. The electronic patient records were reviewed for patients’ demographic parameters, prevalence of possible ADRs and assessment of their preventability. In addition, the extent of formal and required ADR reporting to national registers was studied. Results Approximately 40 percent of the patient population had at least one possible ADR (n = 284). In the multivariable regression model, age and number of drugs were significantly associated with risk of presenting with an ADR (p
Databáze: OpenAIRE