Chronic arsenic toxicity in sheep of Kurdistan province, western Iran
| Autor: | Mehrdad Pourjafar, Zahra Akbari, Afsaneh Seradj, Alireza Rahmani Shahraki, Behnam Keshavarzi, Farid Moore |
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| Rok vydání: | 2014 |
| Předmět: |
Biogeochemical cycle
Anemia Health Toxicology and Mutagenesis Population Aspartate transaminase Biology Iran Toxicology Arsenic Soil Animal science Reference Values Arsenic Poisoning medicine Animals Aspartate Aminotransferases education education.field_of_study Sheep Arsenic toxicity medicine.diagnostic_test business.industry Alanine Transaminase General Medicine Environmental Exposure medicine.disease Pollution Biotechnology Alanine transaminase Toxicity biology.protein business Liver function tests |
| Zdroj: | Archives of environmental contamination and toxicology. 69(1) |
| ISSN: | 1432-0703 |
| Popis: | After the detection of arsenic (As) toxicity in sheep from Ebrahim-abad and Babanazar villages in Kurdistan province, the concentration of this element in drinking water, cultivated soil, alfalfa hay, wool, and blood samples was evaluated. Total As concentrations ranged from 119 to 310 μg/L in drinking water, 46.70–819.20 mg/kg in soil 1.90–6.90 mg/kg in vegetation 1.56–10.79 mg/kg in sheep’s wool, and 86.30–656 μg/L in blood samples. These very high As contents, in all parts of the biogeochemical cycle, exceed the recommended normal range for this element compared with a control area. Results indicate that As has moved through all compartments of the biogeochemical cycle by way of direct or indirect pathways. The present investigation illustrated decreased packed cell volume and hemoglobin in sheep from the As-contaminated zone. It was concluded that sheep from the contaminated areas suffer from anemia. Chronic As exposure of the liver was determined by liver function tests. For this purpose, blood aspartate transaminase (AST) and alanine transaminase (ALT) were measured. The results show that serum ALT and AST activities are increased significantly (p |
| Databáze: | OpenAIRE |
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