Bone and body composition response to testosterone therapy vary according to polymorphisms in the CYP19A1 gene

Autor:	Clifford Qualls, Georgia Colleluori, Reina Armamento-Villareal, Lina E. Aguirre, Vallabh O. Shah, David Robbins, Richard I. Dorin, Irum Zeb Jan, Dennis T. Villareal, Rui Chen
Rok vydání:	2019
Předmět:	Adult Male medicine.medical_specialty Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Single-nucleotide polymorphism Hematocrit Polymorphism Single Nucleotide Article Bone and Bones Body Mass Index Bone remodeling 03 medical and health sciences Absorptiometry Photon Aromatase 0302 clinical medicine Endocrinology Bone Density Internal medicine Genotype medicine Humans Testosterone Prospective Studies Musculoskeletal System Aged Bone mineral Polymorphism Genetic medicine.diagnostic_test biology business.industry Prostate Middle Aged Prostate-Specific Antigen 030220 oncology & carcinogenesis Body Composition biology.protein Lean body mass Bone Remodeling business
Zdroj:	Endocrine
ISSN:	1559-0100 1355-008X
DOI:	10.1007/s12020-019-02008-6
Popis:	PURPOSE: To evaluate the influence of single nucleotide polymorphisms (SNPs) of CYP19A1 on the response and susceptibility to side effects from testosterone therapy. This is a prospective, single-arm study of men with low morning serum testosterone (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e301505e18bab421f45cb9a54c41b564 https://doi.org/10.1007/s12020-019-02008-6 Zobrazit plný text záznamu Full text from SpringerLink