The Effect of Plantaginis Semen Herbal Acupuncture on Rat by Glycerol-Induced Acute Renal Failure
Autor: | Si-Yong Cho, Choon-Ho Song |
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Jazyk: | angličtina |
Rok vydání: | 2000 |
Předmět: |
medicine.medical_specialty
Increased glomerular filtration rate Decreased serum creatinine Plantaginis Semen lcsh:Medicine Semen Hindlimb urologic and male genital diseases Excretion chemistry.chemical_compound Acute renal failure Internal medicine medicine Glycerol Herbal Acupuncture lcsh:Miscellaneous systems and treatments Pharmacology Creatinine business.industry lcsh:R lcsh:RM1-950 lcsh:RZ409.7-999 Shenso(BL23) Endocrinology lcsh:Therapeutics. Pharmacology Complementary and alternative medicine Decreased glomerular filtration rate chemistry business |
Zdroj: | Journal of Pharmacopuncture, Vol 3, Iss 2, Pp 41-54 (2000) |
ISSN: | 2234-6856 2093-6966 |
Popis: | This study was undertaken to determine if Plantaginis Semen Herbal Acupuncture(PSA) has a protective effect against glycerol-induced acute renal failure in rats. Rats were dehydrated for 24hr and then injected with 8 ml/kg of glycerol, one-half of dose in each hindlimb muscle. In experiments for PSA effect, rats received 0.1 ml of PSA extraction in both sides of corresponding Shenso(BL23) of human body for 3 days after injection of glycerol. The experimental group were di vided into the Normal group, the Control group, the PSA group. Glycerol injection decreased glomerular filtration rate and increased urine volume, serum creatinine, BUN level and fractional excretion of glucose Na+, K+ and CI-. These result show that glycerol injection result in acute renal failure. PSA significantly increased glomerular filtration rate and significantly decreased serum creatinine, BUN level and fractional excretion of glucose, NA+ and CI- and as compared Control group. This suggests that PSA could be used in prevention and treatment of acute renalfailure. However, the precise mechanisms of PSA protection remain to be determined. |
Databáze: | OpenAIRE |
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