| Autor: |
A. Vidal-Realpe, R.A. Dueñas-Cuellar, V.E. Niño-Castaño, D.L. Mora-Obando, J.J. Arias-Agudelo, H.J. Bolaños |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Revista de gastroenterologia de Mexico (English). |
| ISSN: |
2255-534X |
| Popis: |
Epstein-Barr virus (EBV) infection is an etiologic factor in EBV-associated gastric carcinoma (EBVaGC). The aim of our study was to describe the clinical and histopathologic characteristics of EBV infection in intestinal-type gastric adenocarcinoma samples.Of 180 paraffin-embedded gastrectomy samples, 28 were studied. Chromogenic in situ hybridization was performed to detect EBV. Sociodemographic and histopathologic data were obtained from the patients' clinical histories.A total of 21.4% of the samples were positive for EBV. The predominant morphologic characteristic was the lace pattern, with dense inflammatory infiltration. Fifty percent of the EBVaGCThe present study describes the clinical and histopathologic characteristics associated with EBVaGC positivity. Those data may aid in the selection of cases that are candidates for analysis through molecular methods aimed at identifying EBV infection in intestinal-type gastric adenocarcinoma. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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