Potential Benefits from 3D Printing and Dental Pulp Stem Cells in Cleft Palate Treatments: An In Vivo Model Study
Autor: | Nieves Cubo Mateo, Amairany Rodríguez Navarrete, Raúl Rosales Ibáñez, Luis María Rodríguez Lorenzo, Leticia Olga Flores Sánchez María |
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Přispěvatelé: | Universidad Nacional Autónoma de México, Rodíiguez-Lorenzo, Luis Maria [0000-0002-4816-1087], Rodíiguez-Lorenzo, Luis Maria |
Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Congenital diseases Dental Pulp Stem Cells business.industry Regeneration (biology) Model study 3D scaffold Dentistry Cleft palates 02 engineering and technology General Medicine 021001 nanoscience & nanotechnology Bone tissue engineering stomatognathic diseases 03 medical and health sciences 030104 developmental biology stomatognathic system In vivo Dental pulp stem cells Medicine Cleft Palate Regeneration 0210 nano-technology business |
Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
Popis: | Cleft palate is one of the most frequent anomalies in the head and neck region. Differ - ent treatments have been used but with each, there are still some disadvantages such as fistulas. The use of a 3D scaffold, with osteoinductive properties, from an easily accessi - ble source, such as dental pulp stem cells, should improve and shorten the treatment of a cleft palate. We conducted a pilot study, in a Vietnamese pig, to evaluate the effectiveness of treating a critical defect of the palate bone, with a 3D Polycaprolactone (PCL) scaffold, in combination with a Beta Tricalcium Phosphate powder (β-TCP) and Pig Dental Pulp Stem Cells (pig DPSC) obtained from the subject pig. PAPIIT, IA209417, UNAM.- Mexico |
Databáze: | OpenAIRE |
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