Is bone mineral density lower in the necrotic lesion in pre-collapse osteonecrosis of the femoral head?
Autor: | Yasuharu Nakashima, Hiroyuki Hatanaka, Ryosuke Yamaguchi, Takeshi Utsunomiya, Shoji Baba, Goro Motomura, Mingjian Xu, Koichiro Kawano, Satoshi Ikemura |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male 0206 medical engineering 02 engineering and technology 03 medical and health sciences Femoral head Young Adult 0302 clinical medicine Absorptiometry Photon Region of interest Bone Density Femur Head Necrosis Reference Values Hounsfield scale medicine Humans Orthopedics and Sports Medicine Dual-energy X-ray absorptiometry Femoral neck Aged Retrospective Studies 030203 arthritis & rheumatology Bone mineral Aged 80 and over medicine.diagnostic_test business.industry Confounding Femur Head Middle Aged 020601 biomedical engineering medicine.anatomical_structure Coronal plane Female Nuclear medicine business Tomography X-Ray Computed |
Zdroj: | Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES. 38(11) |
ISSN: | 1554-527X |
Popis: | The purpose of this study was to clarify whether bone mineral density (BMD) of the necrotic lesion in precollapse osteonecrosis of the femoral head (ONFH) is reduced according to Hounsfield unit (HU) values on computed tomography (CT). The superior one-third of the femoral head in the coronal section was set as the region of interest (ROI) for the measurement of HU values. First, HU values of 101 control participants were assessed to identify relevant confounding factors. Next, the relationship between HU values and BMD on dual-energy X-ray absorptiometry (DXA) was verified. Then the mean HU value of the ROI in patients with pre-collapse ONFH was compared with that in propensity score-matched control participants. Finally, the HU values of the lateral boundary in the patients with and without subsequent collapse were compared. Multivariable analysis showed that both age and BMI were significantly correlated with the HU value, which showed a strong correlation with the BMD of the femoral neck on DXA (r = 0.92). In 25 ONFH patients and 25 propensity-matched control participants, no significant difference was found in the HU value of the ROI (p = .54). The mean HU value of the lateral boundary in patients with subsequent collapse was found to be significantly higher than that in patients without subsequent collapse (p < .01). The assessment of HU values on CT was useful for the evaluation of BMD of the femoral head. The current assessment did not demonstrate reduced bone mineral density of the necrotic lesion in pre-collapse ONFH. |
Databáze: | OpenAIRE |
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