Mesentery lymphoma in a patient with Crohn's disease: An extremely rare entity

Autor: Georgios Gemenetzis, John Chrysikos, Charalampos Seretis, Lagoudianakis E, Andreas Manouras, Nikolaos Koronakis, Apostolos Pappas, Dimitrios Keramidaris
Rok vydání: 2012
Předmět:
Zdroj: International Journal of Surgery Case Reports. 3(7):343-345
ISSN: 2210-2612
DOI: 10.1016/j.ijscr.2012.04.005
Popis: INTRODUCTIONLymphoma is a rare complication of long-standing Crohn's disease. We report a rare case of a diffuse, B-cell non-Hodgkin's lymphoma of the mesentery in a patient receiving treatment for Crohn's disease.PRESENTATION OF CASEA 52 year-old patient presented with abdominal pain, anorexia and postprandial fullness. Abdominal examination revealed a firm mass, extending from the epigastrium to the right iliac fossa. CT scan showed a large intra-abdominal mass with air-fluid levels within, and soft tissue density along its walls, surrounded by distended bowel loops. The patient was scheduled for surgery due to clinical assumption of an intra-abdominal abscess. At laparotomy an ill-defined, lobulated mass with cystic areas was noted rising from the mesentery. Frozen section biopsy of the cystic mass revealed a non-Hodgkin follicle center B-cell lymphoma of the mesentery.DISCUSSIONTo the best of our knowledge, this is an extremely rare case of lymphoma development in the mesentery, in a patient receiving treatment for Crohn's disease. Although the development of abdominal lymphomas can be justified as a possible consequence of the chronic immune-modulating therapy, their location can lead to diagnostic pitfalls.CONCLUSIONAlthough mesentery has scarcely been presented as a potential site of occurrence of abdominal lymphomas in the process of treatment of inflammatory bowel diseases, this rare entity should be considered in the differential diagnosis of intra-abdominal lymphomas in patients with inflammatory bowel disease. In cases where imaging techniques do not provide definitive answers, surgical intervention can safely pose the accurate diagnosis.
Databáze: OpenAIRE