Retrospective study of the functional and oncological outcomes of conformal sphincter preservation operation in the treatment of very low rectal cancer
| Autor: | G Sun, H F Gong, Z Lou, Edgar J B Furnée, G Y Yu, R G Meng, C G Bai, X H Gao, K Zheng, H Zhang, W Zhang |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Neoplasm recurrence China medicine.medical_specialty Disease-free survival medicine.medical_treatment Anal Canal INTERSPHINCTERIC RESECTION Rectal neoplasms Follow-up studies Postoperative complications Ileostomy Margins of excision QUALITY-OF-LIFE ANTERIOR RESECTION COLOANAL ANASTOMOSIS Humans Medicine ABDOMINOPERINEAL RESECTION SAVING RESECTION Coloanal anastomosis Aged Retrospective Studies ANAL-SPHINCTER business.industry Abdominoperineal resection FECAL CONTINENCE Gastroenterology Postoperative complication Syndrome Perioperative Middle Aged Colorectal surgery Surgery Treatment Outcome Local PREOPERATIVE RADIATION-THERAPY Low anterior resection syndrome Resection margin Anal verge Original Article Neoplasm Recurrence Local business |
| Zdroj: | Techniques in Coloproctology Techniques in Coloproctology, 24(10), 1025-1034. SPRINGER-VERLAG ITALIA SRL |
| ISSN: | 1128-045X 1123-6337 |
| Popis: | Background Conformal sphincter preservation operation (CSPO) is a new surgical procedure for very low rectal cancers (within 4–5 cm from the anal verge). CSPO preserves more of the dentate line and distal rectal wall and also avoids injuring nerves in the intersphincteric space, resulting in satisfactory anal function after resection. The aim of this study was to analyze the short-term surgical results and long-term oncological and functional outcomes of CSPO. Methods Consecutive patients with very low rectal cancer, who had CSPO between January 2011 and October 2018 at Changhai Hospital, Shanghai were included. Patient demographics, clinicopathological features, oncological outcomes and anal function were analyzed. Results A total of 102 patients (67 men) with a mean age of 56.9 ± 10.8 years were included. The median distance of the tumor from the anal verge was 3 (IQR, 3–4) cm. Thirty-five patients received neoadjuvant chemoradiation (nCRT). The median distal resection margin (DRM) was 0.5 (IQR, 0.3–0.8) cm. One patient had a positive DRM. All circumferential margins were negative. There was no perioperative mortality. The postoperative complication rate was 19.6%. The median duration of follow-up was 28 (IQR, 12–45.5) months. The local recurrence rate was 2% and distant metastasis rate was 10.8%. The 3-year overall survival and disease-free survival rates were 100% and 83.9%, respectively. The mean Wexner incontinence and low anterior resection syndrome scores 12 months after ileostomy reversal were 5.9 ± 4.3, and 29.2 ± 6.9, respectively. Conclusions For patients with very low rectal cancers, fecal continence can be preserved with CSPO without compromising oncological results. |
| Databáze: | OpenAIRE |
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