Erratum to: Effect of Bayesian-penalized likelihood reconstruction on [13N]-NH3 rest perfusion quantification
| Autor: | Jim O’ Doherty, Daniel R. McGowan, Sally F. Barrington, Carla Abreu |
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| Rok vydání: | 2017 |
| Předmět: |
Rest (physics)
physics of imaging Penalized likelihood medicine.medical_specialty business.industry Bayesian probability 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences N-13 ammonia PET Internal medicine 0103 physical sciences Cardiology Medicine Radiology Nuclear Medicine and imaging Original Article 010306 general physics 0210 nano-technology Cardiology and Cardiovascular Medicine business Perfusion |
| Zdroj: | Journal of Nuclear Cardiology |
| ISSN: | 1532-6551 |
| Popis: | Abstact Objectives Myocardial blood flow (MBF) imaging is used in patients with suspected cardiac sarcoidosis, and also in stress/rest studies. The accuracy of MBF is dependent on imaging parameters such as new reconstruction methodologies. In this work, we aim to assess the impact of a novel PET reconstruction algorithm (Bayesian-penalized likelihood—BPL) on the values determined from the calculation of [13N]-NH3 MBF values. Methods Data from 21 patients undergoing rest MBF evaluation [13N]-NH3 as part of sarcoidosis imaging were retrospectively analyzed. Each scan was reconstructed with a range of BPL coefficients (1-500), and standard clinical FBP and OSEM reconstructions. MBF values were calculated via an automated software routine for all datasets. Results Reconstruction of [13N]-NH3 dynamic data using the BPL, OSEM, or FBP reconstruction showed no quantitative differences for the calculation of territorial or global MBF (P = .97). Image noise was lower using OSEM or BPL reconstructions than FBP and noise from BPL reached levels seen in OSEM images between B = 300 and B = 400. Intrasubject differences between all reconstructions over all patients in respect of all cardiac territories showed a maximum coefficient of variation of 9.74%. Conclusion Quantitation of MBF via kinetic modeling of cardiac rest MBF by [13N]-NH3 is minimally affected by the use of a BPL reconstruction technique, with BPL images presenting with less noise. |
| Databáze: | OpenAIRE |
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