Cholecystitis and cholelithiasis associated with an intramural fasciitis-like proliferation and osseous metaplasia
| Autor: | Tanya A. Rege, Sara O. Vargas |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
Abdominal pain Pathology medicine.medical_specialty medicine.medical_treatment Gallbladder Injury Anemia Sickle Cell Pathology and Forensic Medicine Cholelithiasis medicine Cholecystitis Humans Cholecystectomy Fasciitis Child Cell Proliferation Metaplasia Common bile duct business.industry Gallbladder Ossification Heterotopic General Medicine medicine.disease medicine.anatomical_structure Giant cell Pediatrics Perinatology and Child Health medicine.symptom business |
| Zdroj: | Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 14(1) |
| ISSN: | 1093-5266 |
| Popis: | Fasciitis-like proliferations are said to be uncommon in the viscera; a fasciitis-like pattern of gallbladder injury may not be rare, but to our knowledge it has not been explicitly reported as such in any age group. Osseous metaplasia, or heterotopic bone, in the gallbladder is rare and has not to our knowledge been reported in a pediatric patient. We report a 7-year-old boy with sickle cell disease who presented with right upper quadrant abdominal pain. An ultrasonograph demonstrated a dilated common bile duct with sludge and stones. A cholecystectomy was performed. Grossly the gallbladder showed numerous pigmented choleliths, and histologically there was cholecystitis with a fasciitis-like fibrous proliferation containing scattered osteoclast-like giant cells and an area of osseous metaplasia. This report, describing a pattern that could be termed “cholecystitis ossificans,” expands the histologic spectrum of chronic cholecystitis, a common disease with a poorly understood pathogenesis. |
| Databáze: | OpenAIRE |
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