Matched case-control study to examine association of psoriasis and migratory glossitis in India

Autor: Shri Nivash, Baldeep Kaur Mann, Sanjay Singh
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Indian Journal of Dermatology, Venereology and Leprology, Vol 79, Iss 1, Pp 59-64 (2013)
ISSN: 0378-6323
Popis: Background: Psoriasis is a multifactorial disease. Genetic and environmental factors, which determine the disease epidemiology and clinical spectrum, are heterogeneous in different populations. A few case-control studies from other countries have shown an association between psoriasis and migratory glossitis (MG). The characteristics of the association (e.g. relationship with gender, severity of psoriasis, early- versus late-onset psoriasis, etc.) have not been clearly defined. Aim: To investigate the association of psoriasis and MG by conducting a matched case-control study in India. Methods: The study was conducted on 600 patients with psoriasis and 800 age- and sex-matched controls. Patients were examined for oral lesions and psoriasis severity was assessed by overall severity index (OSI) and psoriasis area and severity index (PASI). We compared the proportions of patients and controls with oral lesions, proportions of male and female patients who had MG, psoriasis severity scores of patients with or without MG, and proportions of early- and late-onset psoriasis patients who had MG. Results: Significantly, more patients had oral lesions than controls (P=0.0013). There was a strong association between psoriasis and MG (P
Databáze: OpenAIRE