Measles in Romania – clinical and epidemiological characteristics of hospitalized measles cases during the first three years of the 2016-ongoing epidemic
Autor: | Anca Streinu-Cercel, Monica Luminos, Maria Dorina Crăciun, Claudia Rîciu, Oana Săndulescu, Daniela Pițigoi, Adrian Streinu-Cercel, Victoria Aramă, Alexandru Rafila, Gheorghiță Jugulete, Angelica Vișan, Anca Drăgănescu |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Surveillance data Adolescent Immunology Infectious and parasitic diseases RC109-216 Comorbidity Biology Microbiology Measles Young Adult 03 medical and health sciences Environmental health Epidemiology medicine Humans vaccine-preventable disease Child Epidemics 030304 developmental biology 0303 health sciences Romania 030306 microbiology Vaccination Infant Newborn Infant Middle Aged medicine.disease measles epidemic Hospitalization Infectious Diseases Case-Control Studies Child Preschool Epidemiological Monitoring Female Parasitology Research Article Research Paper |
Zdroj: | Virulence article-version (VoR) Version of Record Virulence, Vol 11, Iss 1, Pp 686-694 (2020) |
ISSN: | 2150-5608 2150-5594 |
Popis: | A large measles epidemic has been ongoing in Romania and many European countries, since 2016. We report case-based surveillance data for all patients (n = 1371) with laboratory-confirmed and epidemiologically-confirmed measles hospitalized in a major infectious diseases hospital in Bucharest Romania during the first three years of the current measles epidemic (July 2016–July 2019). More than half of the patients (57.6%) had ages below 5 years; 6% (n = 82) had preexisting comorbidities. Only 1.5% of the patients had been fully vaccinated, 5.9% had received only one vaccine dose, while 92.8% had not been vaccinated at all against measles. The rate of measles-related complications was 93.4%; complications occurred more frequently among patients who were not eligible for vaccination due to young age or underlying diseases, and among children, who developed pneumonia and enterocolitis more frequently than adults. The median hospital length-of-stay was 6 days. Eight cases (0.6%) required intensive care and mechanical ventilation, and three deaths (0.2%) were recorded. Measles disproportionately affects patient groups who are not eligible for vaccination. During the current epidemic in Romania, 98.5% of the patients hospitalized for measles had not been vaccinated and among these, 75.7% would have been eligible for vaccination. For the remaining pool of unvaccinated children, supplementary immunization activities are urgently needed. |
Databáze: | OpenAIRE |
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