Challenges to PrEP use and perceptions of urine tenofovir adherence monitoring reported by individuals on PrEP

Autor:	Helen C. Koenig, Linden Lalley-Chareczko, Travis Hunt, Giffin W. Daughtridge, Meghan Swyryn
Rok vydání:	2019
Předmět:	Adult Male medicine.medical_specialty Health (social science) Adolescent Urban Population Social Psychology Tenofovir Anti-HIV Agents Population Human immunodeficiency virus (HIV) Stigma (botany) HIV Infections Urine medicine.disease_cause Health Services Accessibility Medication Adherence Young Adult 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine education Finger prick Philadelphia education.field_of_study 030505 public health business.industry Public Health Environmental and Occupational Health Community Health Centers Phlebotomy Family medicine Adherence monitoring Female Perception Pre-Exposure Prophylaxis 0305 other medical science business medicine.drug
Zdroj:	AIDS Care. 31:1203-1206
ISSN:	1360-0451 0954-0121
Popis:	Maximizing the impact of HIV pre-exposure prophylaxis (PrEP) requires optimizing access and adherence for those at risk of contracting HIV. This study examined challenges to the processes of accessing and adhering to PrEP encountered by participants from a large, U.S. urban clinical center and assessed the utility of objectively monitoring PrEP adherence via urine. Most participants (65%) reported starting PrEP within 1-3 months of hearing about it, although 35% of participants encountered a provider unwilling to prescribe PrEP. Self-reported adherence was high among this population, with remembering to take the medication reported as the major barrier to adherence (44%) rather than cost or stigma. Urine tenofovir (TFV) monitoring was highly acceptable to this population, and participants indicated greater willingness to undergo urine monitoring every 3 months compared to finger prick (dried blood spot), phlebotomy, or hair follicle testing. These findings highlight the importance of focusing efforts toward reducing obstacles to PrEP use and support the use of urine TFV adherence monitoring as a marker of PrEP adherence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dd8b47642f5ddc4ff1c9d49497834d https://doi.org/10.1080/09540121.2019.1587369 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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