Breaking the Excitation-Inhibition Balance Makes the Cortical Network's Space-Time Dynamics Distinguish Simple Visual Scenes
| Autor: | Lars H. Bonde, Michael A. Harvey, Per E. Roland, Lars E. Forsberg |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Visual perception genetic structures Dynamical systems theory Computer science Cognitive Neuroscience media_common.quotation_subject Neuroscience (miscellaneous) Voltage-sensitive dye mechanics of vision lcsh:RC321-571 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Developmental Neuroscience Dynamical systems balanced network Contrast (vision) Computer vision lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Inhibition Original Research Balance (ability) media_common Voltage sensitive dye business.industry voltage sensitive dye Dynamics (mechanics) Mechanics of vision Cerebral cortex dynamical systems inhibition Balanced network 030104 developmental biology Flow (mathematics) cerebral cortex Artificial intelligence Biological system business 030217 neurology & neurosurgery Excitation Neuroscience |
| Zdroj: | Frontiers in Systems Neuroscience Roland, P E, Bonde, L H, Forsberg, L E & Harvey, M A 2017, ' Breaking the excitation-inhibition balance makes the cortical network’s space-time dynamics distinguish simple visual scenes ', Frontiers in Systems Neuroscience, vol. 11, 14 . https://doi.org/10.3389/fnsys.2017.00014 Frontiers in Systems Neuroscience, Vol 11 (2017) |
| ISSN: | 1662-5137 |
| DOI: | 10.3389/fnsys.2017.00014 |
| Popis: | Brain dynamics are often taken to be temporal dynamics of spiking and membrane potentials in a balanced network. Almost all evidence for a balanced network comes from recordings of cell bodies of few single neurons, neglecting more than 99% of the cortical network. We examined the space-time dynamics of excitation and inhibition simultaneously in dendrites and axons over four visual areas of ferrets exposed to visual scenes with stationary and moving objects. The visual stimuli broke the tight balance between excitation and inhibition such that the network exhibited longer episodes of net excitation subsequently balanced by net inhibition, in contrast to a balanced network. Locally in all four areas the amount of net inhibition matched the amount of net excitation with a delay of 125 ms. The space-time dynamics of excitation-inhibition evolved to reduce the complexity of neuron interactions over the whole network to a flow on a low-(3)-dimensional manifold within 80 ms. In contrast to the pure temporal dynamics, the low dimensional flow evolved to distinguish the simple visual scenes. |
| Databáze: | OpenAIRE |
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