Complement receptors C5aR1 and C5aR2 differentially influence bone metabolism

Autor: Hägele, Yvonne, Bergdolt, Stephanie, Matthes, Rebecca, Kovtun, Anna, Ignatius, Anita
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017); 20171024-20171027; Berlin; DOCGR14-359 /20171023/
Popis: Objectives: Activation of the complement system, a crucial arm of innate immunity, leads to the generation of the anaphylatoxin C5a, acting via its receptors C5aR1 and C5aR2. C5aR1 has already been attributed an important role in bone development, regeneration and inflammation, as C5aR1 expression on[for full text, please go to the a.m. URL]
Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017)
Databáze: OpenAIRE