Special report: Noninvasive multi-parameter functional optical imaging of the eye
| Autor: | Darin Nelson, Sara Krupsky, Ayala Pollack, Mordechai Rosner, Ivo Vanzetta, Amiram Grinvald, Michael Belkin, Eyal Aloni |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Diagnostic Imaging Male Early detection Diagnostic Techniques Ophthalmological Retina chemistry.chemical_compound Optical imaging Retinal Diseases Medical imaging Medicine Humans Oximetry Multi parameter Aged Clinical Trials as Topic business.industry Retinal Vessels Retinal Blood flow Oxygen Functional mapping medicine.anatomical_structure chemistry Regional Blood Flow sense organs business Blood Flow Velocity Biomedical engineering |
| Zdroj: | Ophthalmic surgery, lasersimaging : the official journal of the International Society for Imaging in the Eye. 36(1) |
| ISSN: | 1542-8877 |
| Popis: | Advancement in the treatment of blindness depends on the development of new technologies that enable early detection, follow-up, and treatment of disease. The authors describe direct, noninvasive imaging of four parameters: blood flow, blood oximetry, metabolic state, and hidden vasculature, particularly capillaries. These are functional parameters of the retina known to be degraded by retinal disease. The new Retinal Function Imager (Optical Imaging, Ltd., Rehovot, Israel) can image all four parameters as intrinsic reflectance intensity differences over the retina's surface. During the past 2 decades, imaging of small optical signals has been a powerful tool for high-resolution functional mapping in the neocortex. In this article, this technology is applied to the retina and demonstrates a general tool for noninvasively probing retinal function in many modalities. Imaging functional changes before anatomic consequences arise holds promise as a powerful tool for early diagnosis and treatment of retinal disease.[Ophthalmic Surg Lasers Imaging 2005;36:57–66.] |
| Databáze: | OpenAIRE |
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