Multi-wavelength photo-acoustic microscopy in the frequency domain for simultaneous excitation and detection of dyes
| Autor: | Olivier Hugon, Boudewijn van der Sanden, Mehdi Inglebert, Chaouqi Misbah, Eric Lacot, Olivier Jacquin |
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| Přispěvatelé: | OPTIMA, Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] (LIPhy), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), LIPhy-OPTIMA, LIPHY-DYFCOM, Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Materials science
Microscope Optical power 01 natural sciences Article law.invention 010309 optics 03 medical and health sciences chemistry.chemical_compound law 0103 physical sciences Microscopy Medical imaging Irradiation 030304 developmental biology Diode [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics] 0303 health sciences business.industry Atomic and Molecular Physics and Optics eye diseases chemistry Frequency domain Optoelectronics business Methylene blue Biotechnology |
| Zdroj: | Biomedical optics express Biomedical optics express, Optical Society of America-OSA Publishing, 2019, 10 (2), pp.932. ⟨10.1364/boe.10.000932⟩ |
| ISSN: | 2156-7085 |
| Popis: | International audience; An optical-resolution photoacoustic microscope with modulated CW laser diodes allowing multi-channel imaging is presented that can be used for both imaging biological tissues and for targeted photo-dynamic therapy (PDT) varying the optical power and exposure time. The effects of this therapy are immediately monitored in order to optimize the time of irradiation. After the description of the experimental setup, in vitro and in vivo applications are presented on a synthetic sample and on the mouse ear using hemoglobin as endogenous and methylene blue as exogenous dye for imaging and PDT, respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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