Epidemiology and Viral Etiology of the Influenza-Like Illness in Corsica during the 2012–2013 Winter: An Analysis of Several Sentinel Surveillance Systems
| Autor: | Jean Pierre Amoros, Laëtitia Minodier, Guillaume Heuze, Marc Ruello, Christophe Arena, Cécile Souty, Laurent Varesi, Alessandra Falchi |
|---|---|
| Přispěvatelé: | Laboratoire de Virologie EA7310, Université Pascal Paoli (UPP), Observatoire régional de la santé de Corse, Ajaccio, Cellule de l'Institut national de veille sanitaire en région, Ajaccio, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), HAL UPMC, Gestionnaire |
| Rok vydání: | 2014 |
| Předmět: |
Male
Pediatrics Epidemiology medicine.disease_cause Disease Outbreaks 0302 clinical medicine Influenza A virus Medicine and Health Sciences 030212 general & internal medicine Young adult Geography Medical Child Phylogeny Aged 80 and over 0303 health sciences Multidisciplinary Coinfection Incidence (epidemiology) Incidence virus diseases General Medicine Middle Aged 3. Good health Intensive Care Units Research Design Virus Diseases Genetic Epidemiology Child Preschool Epidemiological Methods and Statistics Medicine Female France Seasons General Agricultural and Biological Sciences Research Article Adult medicine.medical_specialty Adolescent Science Molecular Sequence Data Research and Analysis Methods Microbiology History 21st Century Infectious Disease Epidemiology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Young Adult Intensive care Virology Influenza Human medicine Genetics Humans 030304 developmental biology Aged Influenza-like illness Survey Research Population Biology business.industry Infant Newborn Outbreak Biology and Life Sciences Infant medicine.disease Nursing Homes respiratory tract diseases Viral Disease Diagnosis Influenza B virus Survey Methods [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie Emergency medicine Genetics of Disease [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business Sentinel Surveillance |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 6, p e100388 (2014) PLoS ONE, Public Library of Science, 2014, 9 (6), pp.e100388. ⟨10.1371/journal.pone.0100388⟩ PLoS ONE, 2014, 9 (6), pp.e100388. ⟨10.1371/journal.pone.0100388⟩ |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0100388 |
| Popis: | International audience; Influenza-like illness (ILI) surveillance is important to identify circulating and emerging/reemerging strains and unusual epidemiological trends. The present study aimed to give an accurate picture of the 2012–2013 ILI outbreak in Corsica by combining data from several surveillance systems: general practice, emergency general practice, hospital emergency units, intensive care units, and nursing homes. Twenty-eight respiratory viruses were retrospectively investigated from patients in general practice with ILI. Sequence analysis of the genetic changes in the hemagglutinin gene of influenza viruses (A(H1N1)pdm2009, A(H3N2) and B) was performed. The trends in ILI/influenza consultation rates and the relative illness ratios (RIRs) of having an ILI consultation were estimated by age group for the different surveillance systems analyzed. Of the 182 ILI patients enrolled by general practitioners, 57.7% tested positive for influenza viruses. Phylogenetic analyses suggested a genetic drift for influenza B and A(H3N2) viruses. The ILI/influenza surveillance systems showed similar trends and were well correlated. In accordance with virological data, the RIRs of having an ILI consultation were highest among the young (,15 years old) and decreased with age. No clusters of acute respiratory illness were declared by the sentinel nursing homes. This study is noteworthy in that it is the first extensive description of the 2012–2013 ILI outbreak in Corsica as monitored through several surveillance systems. To improve ILI surveillance in Corsica, a consortium that links together the complementary regional surveillance ILI systems described here is being implemented. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|