Methodological Considerations in Designing and Implementing the Harmonized Diagnostic Assessment of Dementia for Longitudinal Aging Stud in India(LASI–DAD)
| Autor: | David E. Bloom, Mekala Padmaja, Prasun Chatterjee, Arvind Jain, G S Shanthi, Judith Saxton, Jorge Jovicich, Sankha Shubhra Chakrabarti, Mathew Varghese, Arthur W. Toga, Ravi Kurup, Perianayagam Arokiasamy, Sarang Pedgaonkar, Parvaiz A Koul, Y Sathyanarayana Raju Yadati, Himanshu Joshi, Eileen M. Crimmins, Sharmistha Dey, Peifeng Hu, Sandy Chien, Joyita Banerjee, John P. John, Brenton Keller, Indrajeet Singh Gambhir, Rashmi Ranjan Mohanty, Debabrata Goswami, Aparajit Ballav Dey, Lalit Sankhe, Kenneth M. Langa, Pranali Khobragade, Aruna Raman, Arunanshu Talukdar, Bas Weerman, Jinkook Lee, Chhaya Rajguru, Urvashi Jain |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Gerontology
Male Aging Population MEDLINE Developing country India Neuropsychological Tests Article 03 medical and health sciences Risk Factors Genetics medicine Dementia Humans Cognitive Dysfunction Longitudinal Studies Prospective Studies education Functional illiteracy Ecology Evolution Behavior and Systematics 030304 developmental biology Demography Aged Protocol (science) 0303 health sciences education.field_of_study 030505 public health Neuropsychology Cognition medicine.disease Magnetic Resonance Imaging Anthropology Female 0305 other medical science Psychology |
| Zdroj: | Biodemography Soc Biol |
| Popis: | The Harmonized Diagnostic Assessment of Dementia for Longitudinal Aging Study in India (LASI-DAD) is a population-representative, prospective cohort study of late-life cognition and dementia. It is part of an ongoing international research collaboration that aims to measure and understand cognitive impairment and dementia risk by collecting a set of cognitive and neuropsychological assessments and informant reports, referred to as the Harmonized Cognitive Assessment Protocol (HCAP). LASI-DAD provides nationally representative data drawn from a subsample of the ongoing Longitudinal Aging Study in India (LASI). One of LASI-DAD's distinctive features is its rich geriatric assessment, including the collection of venous blood samples and brain imaging data for a subsample of respondents. In this paper, we discuss the methodological considerations of developing and implementing the HCAP protocol in India. The lessons we learned from translating and applying the HCAP protocol in an environment where illiteracy and innumeracy are high will provide important insights to researchers interested in measuring and collecting data on late-life cognition and dementia in developing countries. We further developed an innovative blood management system that enables us to follow the collection, transportation, assay, and storage of samples. Such innovation can benefit other population surveys collecting biomarker data. |
| Databáze: | OpenAIRE |
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