Simultaneous assessment of wall motion and coronary flow velocity in the left anterior descending coronary artery during dipyridamole stress echocardiography
| Autor: | Ken-ichi Arimura, Yuichi Nohtomi, Shoichi Kondo, Akira Yamada, Kenji Miyata, Shuichi Okamatsu, Kouichi Kuwata, Tohru Yamawaki, Masaaki Takeuchi, Kazushige Nagasawa |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Vasodilator Agents Constriction Pathologic Anterior Descending Coronary Artery Doppler echocardiography Coronary Angiography Sensitivity and Specificity Constriction Coronary artery disease Internal medicine medicine Stress Echocardiography Humans Radiology Nuclear Medicine and imaging Aged medicine.diagnostic_test business.industry Coronary flow reserve Dipyridamole Middle Aged medicine.disease Coronary Vessels Myocardial Contraction Echocardiography Doppler Stenosis Cardiology Feasibility Studies Female Radiology Cardiology and Cardiovascular Medicine business Blood Flow Velocity medicine.drug |
| Zdroj: | Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 16(5) |
| ISSN: | 0894-7317 |
| Popis: | This study was designed to assess the feasibility and clinical meaning of simultaneous assessment of wall motion and coronary flow velocity (CFV) reserve in the left anterior descending coronary artery (LAD) by transthoracic approach for detecting LAD stenosis during dipyridamole stress echocardiography.Coronary flow reserve plays an important role, which can be evaluated by transthoracic Doppler echocardiography during vasodilator stress.Dipyridamole stress test was performed in 110 patients with known or suspected coronary artery disease. CFV in the distal LAD was obtained at baseline and after dipyridamole infusion, and wall motion was also assessed up to the administration of atropine, if required. All patients underwent quantitative coronary angiography within 2 days of the stress test, and significant LAD stenosis was defined as50% stenosis.The success rate of both measurements was 92%. CFV reserve2 had a higher sensitivity (94% vs 72%, P.01) and a lower specificity (65% vs 95%, P.01) than wall-motion assessment for detecting significant LAD stenosis, and diagnostic accuracy between 2 methods was comparable (81% vs 82%). A total of 69 patients (73%) showed concordant results of the 2 methods, and diagnostic accuracy for detecting significant LAD stenosis was high (94%) in this subset of patients.The simultaneous assessment of CFV and wall motion was feasible in the majority of cases during dipyridamole stress echocardiography. Although diagnostic accuracy between the 2 tests was comparable, concordant results of the 2 methods provided accurate diagnosis in detecting significant LAD stenosis. |
| Databáze: | OpenAIRE |
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