Role of FDG-PET scan in the management of pediatric mature B cell non-Hodgkin’s lymphoma. CCHE experience
| Autor: | Tarek Raafat, Ayda Youssef, Omneya Hassanein, Hany Abdel Rahman, Mohamed Sedky, Walid Omar, Asmaa Hamoda, Emad Moussa |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Male
medicine.medical_treatment Mature B-Cell 030218 nuclear medicine & medical imaging 0302 clinical medicine Positron Emission Tomography Computed Tomography hemic and lymphatic diseases Materials Chemistry Child Medicine(all) lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Hospitals Pediatric Burkitt Lymphoma medicine.anatomical_structure Mature B-Cell Non-Hodgkin's Lymphoma Child Preschool 030220 oncology & carcinogenesis Egypt Female Lymphoma Large B-Cell Diffuse Radiology Pediatric NHL medicine.medical_specialty Adolescent Cancer Care Facilities lcsh:RC254-282 Sensitivity and Specificity 03 medical and health sciences Fluorodeoxyglucose F18 Predictive Value of Tests medicine CCHE Humans B cell Mature B cell Retrospective Studies Chemotherapy business.industry Infant Cancer Retrospective cohort study PET scan medicine.disease Lymphoma Radiography Radiopharmaceuticals Tomography X-Ray Computed business Nuclear medicine |
| Zdroj: | Journal of the Egyptian National Cancer Institute, Vol 28, Iss 2, Pp 95-99 (2016) |
| ISSN: | 1110-0362 |
| DOI: | 10.1016/j.jnci.2016.03.003 |
| Popis: | Aim of work: To evaluate the sensitivity (Se), specificity (Sp), and predictive values (PV) of PET scan during management of pediatric mature B cell non-Hodgkin’s lymphoma (NHL) in comparison with conventional computed tomography (CT) scan. Patients and methods: A retrospective study enrolled on pediatric NHL patients at Children Cancer Hospital Egypt (CCHE) during the period from July 2007 to the end of June 2013. Results: For 115 pediatric patients diagnosed with mature B cell NHL, 152 PET and 152 CT scans were done simultaneously. Median age was 5.7 years. They were 85 males (74%) and 30 females (26%). One hundred twenty six scans (82.9%) were done for 100 (87%) Burkitt lymphoma (BL) patients, while 26 scans (17.1%) were done for 15 (13.0%) patients with diffuse large B cell NHL (DLBC). Nineteen examination (12.5%) were done before starting chemotherapy (group 1), 107 (70.3%) at time of evaluation (group 2), and 26 (17.1%) during follow up (group C). Overall sensitivity was 91.6% for PET and 70.0% for conventional CT (p = 0.02). Specificity was 84.1% for PET and 58.9% for CT (p |
| Databáze: | OpenAIRE |
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