Clinical performance of digital cervicography and cytology for cervical cancer screening in HIV-infected women in Lusaka, Zambia
| Autor: | Groesbeck P. Parham, Jeffrey S. A. Stringer, Allen C. Bateman, Theresa Nkole, Carla J. Chibwesha, Mulindi H. Mwanahamuntu, Michael L. Hicks, Sharon Kapambwe, Jacqueline Mulundika, Sten H. Vermund, Vikrant V. Sahasrabuddhe, Aaron Shibemba, Krista S. Pfaendler, Katundu Katundu |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Population Cytological Techniques Uterine Cervical Neoplasms Zambia HIV Infections Sensitivity and Specificity Article Young Adult Cytology medicine Humans Mass Screening Pharmacology (medical) education Acetic Acid Gynecology Cervical cancer education.field_of_study Obstetrics business.industry Optical Imaging Clinical performance Cancer Middle Aged medicine.disease Uterine Cervical Dysplasia Confidence interval Squamous intraepithelial lesion Infectious Diseases Colposcopy Female Cervicography business |
| Zdroj: | Journal of acquired immune deficiency syndromes (1999). 67(2) |
| ISSN: | 1944-7884 |
| Popis: | Although there is a growing literature on the clinical performance of visual inspection with acetic acid in HIV-infected women, to the best of our knowledge, none have studied visual inspection with acetic acid enhanced by digital cervicography. We estimated clinical performance of cervicography and cytology to detect cervical intraepithelial neoplasia grade 2 or worse. Sensitivity and specificity of cervicography were 84% [95% confidence interval (CI): 72 to 91) and 58% (95% CI: 52 to 64). At the high-grade squamous intraepithelial lesion or worse cutoff for cytology, sensitivity and specificity were 61% (95% CI: 48 to 72) and 58% (95% CI: 52 to 64). In our study, cervicography seems to be as good as cytology in HIV-infected women. |
| Databáze: | OpenAIRE |
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