Ocular Sarcoidosis
| Autor: | Roger Grimson, Harvey Checkoway, David J. Ballard, John C. Merritt, Patricia Mower |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Male Risk medicine.medical_specialty Adolescent Eye Diseases Sarcoidosis Black People Newly diagnosed Tobacco industry General Biochemistry Genetics and Molecular Biology Sex Factors History and Philosophy of Science Environmental risk Internal medicine Epidemiology North Carolina medicine Humans Child business.industry General Neuroscience Age Factors Case-control study Middle Aged medicine.disease Occupational Diseases Female business Uveitis Ocular sarcoidosis |
| Zdroj: | Annals of the New York Academy of Sciences. 465:619-624 |
| ISSN: | 1749-6632 0077-8923 |
| DOI: | 10.1111/j.1749-6632.1986.tb18538.x |
| Popis: | A case-control study was conducted to investigate possible environmental risk factors for ocular sarcoidosis. The factors studied were exposures to pine products and occupational histories of employment in the tobacco, lumber, and textile industries. The exposure histories of 29 female and 15 male cases, patients with newly diagnosed ocular sarcoidosis that were attending the Glaucoma/Uveitis Clinic of the North Carolina Memorial Hospital, were compared to those of 110 female and 28 male controls selected from out-patient clinics. Elevated risks for sarcoidosis were detected among those females that were exposed to burning pine or were employed in the tobacco industry. For males, positive associations were observed for chewing pine products and for employment in the lumber and textile industries. These preliminary data are consistent with incomplete phagocytic clearance of nonbiodegradable foreign bodies present within our environment that may become antigenic to the immunologically susceptible host. Confirmation of refutation of these hypotheses awaits additional clinical and epidemiological research within the sarcoidosis belt. |
| Databáze: | OpenAIRE |
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