Is 6-month GRACE risk score a useful tool to predict stroke after an acute coronary syndrome?
| Autor: | María Castiñeira-Busto, Andrea López-López, Emad Abu-Assi, Sergio Raposeiras-Roubín, Alfredo Redondo-Diéguez, Noelia Bouzas-Cruz, José Ramón González-Juanatey, José María García-Acuña, Santiago Gestal-Romaní, Eva Maria Pereira Lopez, Cristina Cambeiro-González, Belén Álvarez-Álvarez, Ozoda Saidhodjayeva |
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| Rok vydání: | 2014 |
| Předmět: |
Pediatrics
medicine.medical_specialty Acute coronary syndrome Framingham Risk Score business.industry medicine.medical_treatment Percutaneous coronary intervention Retrospective cohort study Atrial fibrillation Coronary Artery Disease medicine.disease Coronary artery disease Internal medicine medicine Cardiology Sinus rhythm cardiovascular diseases Cardiology and Cardiovascular Medicine business Stroke |
| Zdroj: | Open Heart |
| ISSN: | 2053-3624 |
| DOI: | 10.1136/openhrt-2014-000123 |
| Popis: | Objectives The risk of stroke after an acute coronary syndrome (ACS) has increased. The aim of this study was to do a comparative validation of the 6-month GRACE (Global Registry of Acute Coronary Events) risk score and CH2DS2VASc risk score to predict the risk of post-ACS ischaemic stroke. Methods This was a retrospective study carried out in a single centre with 4229 patients with ACS discharged between 2004 and 2010 (66.9±12.8 years, 27.9% women, 64.2% underwent percutaneous coronary intervention). The primary end point is the occurrence of an ischaemic stroke during follow-up (median 4.6 years, IQR 2.7–7.1 years). Results 184 (4.4%) patients developed an ischaemic stroke; 153 (83.2%) had sinus rhythm and 31 (16.9%) had atrial fibrillation. Patients with stroke were older, with higher rates of hypertension, diabetes, previous stroke and previous coronary artery disease. The HR for CHA2DS2VASc was 1.36 (95% CI, 1.27 to 1.48, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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