Quality Control in Nucleic Acid Amplification Methods: Use of Elementary Probability Theory
| Autor: | Daniel S. Shapiro |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Quality Control
Microbiology (medical) Quantitative Biology::Biomolecules Models Statistical Binomial (polynomial) Gene Amplification Negative control Chlamydia trachomatis Biology Poisson distribution Communicable Diseases Polymerase Chain Reaction Binomial distribution symbols.namesake Quality (physics) Genetic Techniques Probability theory Virology Nucleic acid symbols Humans Applied mathematics Artifacts Control (linguistics) Probability |
| Zdroj: | Journal of Clinical Microbiology. 37:848-851 |
| ISSN: | 1098-660X 0095-1137 |
| Popis: | Since it is not possible to state with certainty that contamination has occurred during a nucleic acid amplification assay in the absence of a positive result for a negative control, methods of elementary probability theory are used to illustrate how to identify those runs in which the possibility of contamination should be considered. The use of binomial and Poisson distributions and an analysis of clusters are presented with illustrative examples to demonstrate their use. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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