Late gestation predictors of a postnatal biventricular circulation after fetal aortic valvuloplasty
| Autor: | Lynn A. Sleeper, Meaghan J Beattie, Louise Wilkins-Haug, Kevin G. Friedman, Ryan Callahan, Carol B. Benson, Minmin Lu, Monika Drogosz, Aaron R. Prosnitz, Terra Lafranchi, Audrey C. Marshall, Wayne Tworetzky |
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| Rok vydání: | 2021 |
| Předmět: |
Balloon Valvuloplasty
Male 0301 basic medicine Aortic arch medicine.medical_specialty medicine.medical_treatment Hemodynamics Gestational Age 030105 genetics & heredity Hypoplastic left heart syndrome Cohort Studies 03 medical and health sciences Fetus 0302 clinical medicine Pregnancy medicine.artery Internal medicine medicine Humans Genetics (clinical) Retrospective Studies Foramen ovale (heart) 030219 obstetrics & reproductive medicine Ejection fraction business.industry Obstetrics and Gynecology Aortic Valve Stenosis medicine.disease Aortic valvuloplasty Stenosis Logistic Models medicine.anatomical_structure Blood Circulation Cardiology Female business |
| Zdroj: | Prenatal Diagnosis. 41:479-485 |
| ISSN: | 1097-0223 0197-3851 2000-2017 |
| DOI: | 10.1002/pd.5885 |
| Popis: | OBJECTIVES Fetal aortic valvuloplasty (FAV) for severe aortic stenosis (AS) has shown promise in averting progression to hypoplastic left heart syndrome. After FAV, predicting which fetuses will achieve a biventricular (BiV) circulation after birth remains challenging. Identifying predictors of postnatal circulation on late gestation echocardiography will improve parental counseling. METHODS Liveborn patients who underwent FAV and had late gestation echocardiography available were included (2000-2017, n = 96). Multivariable logistic regression and classification and regression tree analysis were utilized to identify independent predictors of BiV circulation. RESULTS Among 96 fetuses, 50 (52.1%) had BiV circulation at the time of neonatal discharge. In multivariable analysis, independent predictors of biventricular circulation included left ventricular (LV) long axis z-score (OR 3.2, 95% CI 1.8-5.7, p |
| Databáze: | OpenAIRE |
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