Occurrence of Toxoplasma gondii antibodies and associated risk factors in women in selected districts of Punjab province, Pakistan
| Autor: | Iahtasham Khan, Haroon Ahmed, Anam Iftikhar, Abdul Maalik, Tahir Mahmood Khan, Shahzad Ali, Zona Amjad |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
0301 basic medicine Binomial regression 030231 tropical medicine Population Antibodies Protozoan Biology Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Risk Factors Seroepidemiologic Studies Environmental health parasitic diseases Prevalence medicine Humans Pakistan education Socioeconomic status Aged Aged 80 and over education.field_of_study Toxoplasma gondii Middle Aged 030108 mycology & parasitology biology.organism_classification medicine.disease Confidence interval Toxoplasmosis Cross-Sectional Studies Logistic Models Infectious Diseases Pregnancy Complications Parasitic Female Animal Science and Zoology Parasitology Toxoplasma Research Article Blood sampling |
| Zdroj: | Parasitology |
| ISSN: | 1469-8161 0031-1820 |
| DOI: | 10.1017/s0031182020000967 |
| Popis: | Toxoplasmosis is a parasitic zoonotic disease caused by Toxoplasma (T.) gondii. Limited data are available on the occurrence of T. gondii in women especially pregnant women in Pakistan. The present study aimed to determine the occurrence and risk factors associated with T. gondii in pregnant and non-pregnant women in Punjab Province, Pakistan. A cross-sectional study was conducted and 593 samples were collected from pregnant (n = 293) and non-pregnant (n = 300) women of District Headquarter Hospitals of Chiniot, Faisalabad, Jhang and Okara, Pakistan. Data related to demographic parameters and risk factors were collected using a pretested questionnaire on blood sampling day. Serum samples were screened for antibodies (IgG) against T. gondii using ELISA. A univariant and binomial logistic regression was applied to estimate the association between seropositive and explanatory variables considering the 95% confidence interval. P value ⩽0.05 was considered statistically significant for all analysis. Out of 593, 44 (7.42%) women were seropositive for T. gondii IgG antibodies. Occupation, age, sampling location, socioeconomic status, contact with cat, pregnancy status and trimester of pregnancy were significantly associated with seropositivity for T. gondii antibodies. Location and trimester of pregnancy were identified as potential risk factors for T. gondii seropositivity based on binomial logistic regression. Toxoplasma gondii is prevalent in pregnant and non-pregnant women. Therefore, now a necessitated awareness is required to instruct the individuals about these infectious diseases (toxoplasmosis) and their control strategies to maintain the health of human population. Moreover, health awareness among public can help the minimization of T. gondii infection during pregnancy and subsequent risk of congenital toxoplasmosis. |
| Databáze: | OpenAIRE |
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