Severe Neuroexcitatory Reaction: A Rare and Underrecognized Life-Threatening Complication of Propofol-Induced Anesthesia
| Autor: | Manoëlle Godio, Grégoire Gex, Linos Pantelakis, Vincent Alvarez |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Hyperthermia
medicine.diagnostic_test business.industry Jerky movements Case Reports medicine.disease 03 medical and health sciences 0302 clinical medicine Bronchoscopy Intensive care Anesthesia medicine Neurology (clinical) Sarcoidosis 030223 otorhinolaryngology Complication Propofol business Drug toxicity 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Neurohospitalist |
| ISSN: | 1941-8752 1941-8744 |
| DOI: | 10.1177/1941874420929536 |
| Popis: | We describe a case of severe neuroexcitatory reaction with hyperthermia after administration of propofol in a 43-year-old patient suspected of a relapse of sarcoidosis who underwent bronchoscopy. This resulted in a lengthy stay in intensive care and long-term neuropsychological impairment. A review of the literature shows that severe neuroexcitatory symptoms (seizure-like phenomena, abnormal hypertonic, and/or jerky movements) occur rarely after propofol administration and may be life-threatening. Due to the paucity of data, the treatment is mostly empirical. The diagnosis can also be delayed owing to underrecognition. We conclude that health practitioners who frequently use propofol should be aware of this specific manifestation of drug toxicity, which albeit rare can be devastating for the patient. |
| Databáze: | OpenAIRE |
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