Mitochondrial DNA damage in the hair bulb: can it be used as a noninvasive biomarker of local exposure to low LET ionizing radiation?
| Autor: | Dávid Kis, Tuomas Virén, Géza Sáfrány, Tünde Szatmári, Katalin Lumniczky, Jan Seppälä, Rita Hargitai, Jukka Luukkonen, Sisko Salomaa, K. Vuolukka, Päivi Roivainen |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Mitochondrial DNA Long pcr DNA Mitochondrial 030218 nuclear medicine & medical imaging Ionizing radiation 03 medical and health sciences Mice 0302 clinical medicine Biodosimetry Medicine Animals Humans Radiology Nuclear Medicine and imaging Linear Energy Transfer Noninvasive biomarkers Aged Radiological and Ultrasound Technology business.industry Bulb Mice Inbred C57BL Biomarker 030220 oncology & carcinogenesis Cancer research Female business Hair Follicle Biomarkers DNA Damage |
| Zdroj: | International journal of radiation biology. 96(4) |
| ISSN: | 1362-3095 |
| Popis: | Purpose: Our aim was to evaluate whether mitochondrial DNA (mtDNA) damage in hair bulbs could be a suitable biomarker for the detection of local exposure to ionizing radiation.Materials and methods... |
| Databáze: | OpenAIRE |
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