Subclinical left ventricular systolic dysfunction detected by two-dimensional speckle tracking echocardiography in patients with pheochromocytoma and paraganglioma and preserved ejection fraction
| Autor: | Jing Ping Sun, Han Zhong Li, Wen Ling Zhu, Zheng Pei Zeng, Jin Ji, Li Ding, Ligang Fang |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart Ventricles Cardiomyopathy Speckle tracking echocardiography Pheochromocytoma 030204 cardiovascular system & hematology Paraganglioma Norepinephrine (medication) Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Pressure overload Ejection fraction business.industry medicine.disease Blood pressure Echocardiography Cardiology Female Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Echocardiography. 35:184-189 |
| ISSN: | 0742-2822 |
| Popis: | BACKGROUND Excessive catecholamine leads to pressure overload and left ventricular (LV) remodeling. The goal of this study was to explore subclinical LV systolic dysfunction and the mechanism of preserved left ventricular ejection fraction (LVEF) in patients with pheochromocytoma and paraganglioma using two-dimensional speckle tracking echocardiography. METHODS A total of 48 patients with pheochromocytoma and paraganglioma and preserved LVEF and 38 age- and gender-matched volunteers were studied. Echocardiographic parameters including LVEF, and global peak longitudinal and circumferential strains were measured. The correlation between echocardiographic parameters and blood pressure as well as biochemical parameters was analyzed. RESULTS LVEF was similar between patients with pheochromocytoma and paraganglioma and controls. The amplitude of LV longitudinal strain was decreased, and the amplitude of LV circumferential strain was increased in the pheochromocytoma and paraganglioma group (P = .003 and P = .009). LV mass index and blood pressure were positively correlated with 24-hour urinary norepinephrine (r = .696, P |
| Databáze: | OpenAIRE |
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