Nontuberculosis mycobacterial infections at a specialized tuberculosis treatment centre in the Republic of Korea

Autor: Hwa Young Choi, Moran Ki, Hee Jung Yoon
Rok vydání: 2016
Předmět:
Male
Epidemiology
0302 clinical medicine
Hospitals
Urban
Prevalence
Infection control
030212 general & internal medicine
education.field_of_study
Surveillance
biology
Incidence (epidemiology)
Incidence
Nontuberculous Mycobacteria
Middle Aged
Mycobacterium avium Complex
Infectious Diseases
Female
medicine.symptom
Research Article
Adult
medicine.medical_specialty
Tuberculosis
Seoul
Mycobacterium avium-intracellulare infection
Population
Mycobacterium Infections
Nontuberculous
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Internal medicine
Republic of Korea
medicine
Humans
lcsh:RC109-216
education
Aged
Mycobacterium avium-intracellulare Infection
Retrospective Studies
Korea
business.industry
Sputum
medicine.disease
biology.organism_classification
bacterial infections and mycoses
030228 respiratory system
Immunology
Nontuberculous mycobacteria
business
Zdroj: BMC Infectious Diseases
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-6 (2017)
ISSN: 1471-2334
Popis: Background The incidence of nontuberculous mycobacteria (NTM) infections is increasing worldwide, however formal evaluations of the epidemiology of NTM infections are limited. Understanding the trends and true prevalence of NTM is a major priority for optimizing infection control programmes and resources. The purpose of this study was to investigate the epidemiology, clinical manifestations, and radiologic findings in NTM-infected patients at specialized Tuberculosis (Tb) treatment centre in South Korea, which is endemic to Tb, and find solutions to control NTM infections. Methods A retrospective descriptive study was conducted among patients who were diagnosed with NTM from November 2011 to January 2016 at Seoul Metropolitan Government Seobuk hospital, Korea, using medical records and chest radiography results. Prevalence of NTM using national health insurance data was compared to the prevalence and incidence of Tb using National statistics data. Results The age- and sex- adjusted prevalence of NTM infection per 100,000 population increased between 2009 (9.4) and 2016 (36.1). However, the prevalence and incidence of Tb per 100,000 population decreased from 106.5 to 74.4, and 81.2 to 61.8, respectively. In total, 64 patients (37 [57.8%] men) were enrolled in the study. Among 33 (51.6%) patients with slowly growing nontuberculous mycobacteria (SGM) infection, 29 were detected with Mycobacterium avium complex (n = 13, M. avium; n = 16, M. intracellulare), and 4 with M. kansasii. Among 31 (48.4%) patients with rapidly growing nontuberculous mycobacteria (RGM) infection, 27 and 4 patients were detected with M. abscessus complex and M. fortuitum complex, respectively. RGM patients were more likely to have current Tb (P = 0.041), cough (P
Databáze: OpenAIRE
Externí odkaz: