Nontuberculosis mycobacterial infections at a specialized tuberculosis treatment centre in the Republic of Korea
Autor: | Hwa Young Choi, Moran Ki, Hee Jung Yoon |
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Rok vydání: | 2016 |
Předmět: |
Male
Epidemiology 0302 clinical medicine Hospitals Urban Prevalence Infection control 030212 general & internal medicine education.field_of_study Surveillance biology Incidence (epidemiology) Incidence Nontuberculous Mycobacteria Middle Aged Mycobacterium avium Complex Infectious Diseases Female medicine.symptom Research Article Adult medicine.medical_specialty Tuberculosis Seoul Mycobacterium avium-intracellulare infection Population Mycobacterium Infections Nontuberculous lcsh:Infectious and parasitic diseases 03 medical and health sciences Internal medicine Republic of Korea medicine Humans lcsh:RC109-216 education Aged Mycobacterium avium-intracellulare Infection Retrospective Studies Korea business.industry Sputum medicine.disease biology.organism_classification bacterial infections and mycoses 030228 respiratory system Immunology Nontuberculous mycobacteria business |
Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-6 (2017) |
ISSN: | 1471-2334 |
Popis: | Background The incidence of nontuberculous mycobacteria (NTM) infections is increasing worldwide, however formal evaluations of the epidemiology of NTM infections are limited. Understanding the trends and true prevalence of NTM is a major priority for optimizing infection control programmes and resources. The purpose of this study was to investigate the epidemiology, clinical manifestations, and radiologic findings in NTM-infected patients at specialized Tuberculosis (Tb) treatment centre in South Korea, which is endemic to Tb, and find solutions to control NTM infections. Methods A retrospective descriptive study was conducted among patients who were diagnosed with NTM from November 2011 to January 2016 at Seoul Metropolitan Government Seobuk hospital, Korea, using medical records and chest radiography results. Prevalence of NTM using national health insurance data was compared to the prevalence and incidence of Tb using National statistics data. Results The age- and sex- adjusted prevalence of NTM infection per 100,000 population increased between 2009 (9.4) and 2016 (36.1). However, the prevalence and incidence of Tb per 100,000 population decreased from 106.5 to 74.4, and 81.2 to 61.8, respectively. In total, 64 patients (37 [57.8%] men) were enrolled in the study. Among 33 (51.6%) patients with slowly growing nontuberculous mycobacteria (SGM) infection, 29 were detected with Mycobacterium avium complex (n = 13, M. avium; n = 16, M. intracellulare), and 4 with M. kansasii. Among 31 (48.4%) patients with rapidly growing nontuberculous mycobacteria (RGM) infection, 27 and 4 patients were detected with M. abscessus complex and M. fortuitum complex, respectively. RGM patients were more likely to have current Tb (P = 0.041), cough (P |
Databáze: | OpenAIRE |
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