Interstitial-cell tumor of the testis: report of two cases

Autor: Joseph Mendeloff, Simon Krantz, John A. Ward, Earl Haltiwanger
Rok vydání: 1960
Předmět:
Zdroj: The Journal of clinical endocrinology and metabolism. 20
ISSN: 0021-972X
Popis: Two cases of interstitial-cell tumor of the testis with gynecomastia in adults are reported. In Case 1 a metastatic lesion developed in the area of the pedicle of the left kidney. Urinary 17-ketosteroid excretion increased to exceedingly high levels. Urinary estrogens were markedly increased whereas pituitary gonadotropins were undetectable at 6.6 mouse units. 17-Hydroxysteroids remained normal until four months prior to death. Hypertension developed about fifteen months prior to death, which occurred five years after removal of the original tumor and three years after the first evidence of intra-abdominal metastatic disease. Case 2 was operated on successfully and the patient is in apparent good health ten years after surgery. INTERSTITIAL-CELL tumors of the testis are relatively rare. They comprised only 1.2 per cent of Dixon and Moore's (1) series of 990 testicular tumors. Generally these tumors are benign. However, in a recent survey of the literature, Dalgaard and Hesselberg (2) tabulated ov...
Databáze: OpenAIRE