Lesion neuroanatomy of the Sustained Attention to Response task
| Autor: | Ronald R. Peeters, Pascal Molenberghs, Hanne Schoofs, Patrick Dupont, Céline R. Gillebert, Rik Vandenberghe |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Cognitive Neuroscience Experimental and Cognitive Psychology Audiology Brain mapping Functional Laterality Brain Ischemia Executive Function Behavioral Neuroscience Neural Pathways Reaction Time medicine Humans Attention Prefrontal cortex Anterior cingulate cortex Aged Aged 80 and over Cerebral Cortex Brain Mapping medicine.diagnostic_test Attentional control Neuropsychology Brain Neuropsychological test Middle Aged Stroke medicine.anatomical_structure Frontal lobe Case-Control Studies Go/no go Female Psychology Neuroscience Psychomotor Performance |
| Zdroj: | Neuropsychologia. 47:2866-2875 |
| ISSN: | 0028-3932 |
| DOI: | 10.1016/j.neuropsychologia.2009.06.012 |
| Popis: | The Sustained Attention to Response task is a classical neuropsychological test that has been used by many centres to characterize the attentional deficits in traumatic brain injury, ADHD, autism and other disorders. During the SART a random series of digits 1-9 is presented repeatedly and subjects have to respond to each digit (go trial) except the digit '3' (no-go trial). Using voxel-based lesion symptom mapping (VLSM) in a consecutive series of 44 ischemic unifocal non-lacunar hemispheric stroke patients we determined the neuroanatomy of 4 SART parameters: commission and omission error rate, reaction time variability and post-error slowing. Lesions of the right inferior frontal gyrus significantly increased commission error rate. Lesions of the middle third of the right inferior frontal sulcus (IFS) reduced post-error slowing, a measure of how well subjects can utilize errors to adjust cognitive resource allocation. Omissions and reaction time variability had less localising value in our sample. To conclude, commission errors and post-error slowing in the SART mainly probe right inferior frontal integrity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect