Measles infection causing Bacillus Calmette-Guérin reactivation: a case report
| Autor: | Anand Mohan, Ling Yin Huang, Kev Shiau Chong Lim, Sobana Muthuvelu, Shi Tying Chin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Erythema Case Report Mucocutaneous Lymph Node Syndrome Measles Measles virus 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Bacillus Calmette-Guérin Maculopapular rash medicine Humans 030212 general & internal medicine Pediatrics Perinatology and Child Health biology Kawasaki disease business.industry lcsh:RJ1-570 Infant lcsh:Pediatrics medicine.disease biology.organism_classification Reactivation Dermatology Morbilliform Rash Pediatrics Perinatology and Child Health biology.protein BCG Vaccine medicine.symptom Antibody business |
| Zdroj: | BMC Pediatrics, Vol 19, Iss 1, Pp 1-5 (2019) BMC Pediatrics |
| ISSN: | 1471-2431 |
| Popis: | Background Reactivation of the Bacillus Calmette-Guérin (BCG), manifesting as erythema, induration, ulceration or crust formation at a previous BCG inoculation site, is a common and highly specific feature of Kawasaki disease (KD). We report the unusual finding of BCG reactivation in an infant with laboratory-confirmed measles. Case presentation A previously healthy 7-month old infant presented initially with fever, cough and coryza, and subsequently developed Koplik’s spots followed by a typical morbilliform skin rash. There was significant contact history with a household relative who had recently been diagnosed with measles. On examination, a 2.5 cm area of erythema and induration was seen at the previous BCG inoculation site, in addition to the widespread maculopapular rash. No other clinical features of KD were present. Measles virus was isolated from the throat swab and measles antibodies (IgM) were present in the serum. The patient recovered completely with oral vitamin A and supportive therapy, and had normal echocardiography examination on follow up. Conclusions This case report highlights the rare finding of BCG reactivation in a child with confirmed measles infection, and suggests that this clinical manifestation may occasionally occur in children with infections or conditions other than KD. |
| Databáze: | OpenAIRE |
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