The role of specific Toxoplasma gondii molecules in manipulation of innate immunity
| Autor: | Angela M. Pollard, Laura J. Knoll, Dana G. Mordue |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Lipoxygenase
chemical and pharmacologic phenomena Article Cyclophilins Profilins Immune system Immunity parasitic diseases medicine Parasite hosting Animals HSP70 Heat-Shock Proteins Innate immune system biology Toll-Like Receptors Toxoplasma gondii biochemical phenomena metabolism and nutrition biology.organism_classification medicine.disease Toxoplasmosis Immunity Innate Infectious Diseases Toxoplasmosis Animal Immunology Myeloid Differentiation Factor 88 Parasitology Signal transduction Toxoplasma Signal Transduction |
| Popis: | Infection with the parasite Toxoplasma gondii stimulates an innate immune response in the host. T. gondii also induces alterations in infected monocytes and dendritic cells that probably contribute to its ability to disseminate and ultimately to establish persistent infection. Recent progress has linked specific parasite molecules to immune stimulation or the ability of the parasite to subvert intracellular signaling pathways in infected cells to evade immunity. |
| Databáze: | OpenAIRE |
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